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Biomolecular Deficit and Immunosenescence

Biomolecular Deficit:
TELOMERE SHORTENING
ALTERED DNA METHYLATION
DNA MISMATCH ​ MITOCHONDRIA
FAILURE INCREASED OXIDATION
STEM CELL DECLINE
IMMUNE RESPONSE
DETERIORATION
Immunosenescence:
TISSUE DEGENERATION
FUNCTIONAL DECLINE
MULTI-ORGAN FAILURE